Kappa opioid receptor:Galphai protein in complex with inverse agonist JDTic

Kappa opioid receptor:Galphai protein in complex with inverse agonist JDTic Descriptor: (3R)-7-hydroxy-N-{(2S)-1-[(3R,4R)-4-(3-hydroxyphenyl)-3,4-dimethylpiperidin-1-yl]-3-methylbutan-2-yl}-1,2,3,4-tetrahydroisoquinoline-3-carboxamide, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... Authors: Gati, C, Motiwala, Z, Tyson, A.S, Styrpejko, D, Han, G.W, Khan, S, Ramos-Gonzalez, N, Shenvi, R, Majumdar, S. Deposit date: 2024-01-31 Release date: 2025-01-15 Last modified: 2025-07-09 Method: ELECTRON MICROSCOPY (3 Å) Cite: Molecular mechanisms of inverse agonism via kappa-opioid receptor-G protein complexes. Nat.Chem.Biol., 21, 2025