Assessing The Cost-Effectiveness of Sleep Interventions For The Treatment of Depression and Insomnia Within The Australian Context

Recent studies show that conventional treatment for comorbid insomnia and depression, which focuses mainly on depression, has limited effectiveness. Cognitive behavioral therapy for insomnia (CBT-I) improves both insomnia and depressive symptoms, but evidence on its cost-effectiveness remains limited. This thesis used a stepped approach, including five studies, to assess the cost-effectiveness of CBT-I. The key finding is that CBT-I, when used concurrently with antidepressants or added to treatment-as-usual for depression, was cost-effective in the Australian context. Treating both conditions was found to significantly improve quality of life, reduce healthcare costs, and enhance work productivity compared to treating depression alone.