IKAROS modulates CD19 surface expression and CD19-directed CAR-T response [ATAC-seq]
收藏NIAID Data Ecosystem2026-05-02 收录
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To elucidate how IKAROS modulates CD19 surface expression in B cell acute lymphoblastic leukemic cells, we analyzed chromatin landscape profile from isogenic IKAROS wild type (WT) or knock down (KD) B-ALL cell lines. Human B-ALL cell lines (NALM6, REH and SUP-B15) were transduced with IKZF1-specific or scramble shRNA expressing lentivirus. 72 hours post transduction, we compared their chromatin landscape profiles through ATAC-seq.
创建时间：
2025-04-30
