A549 cells were used to examine the effect of AX0085, a novel kinase inhibitor. In particular, its effect in reversing the effect of interferon gamma was determined. Combination treatment of two reage

NIAID Data Ecosystem20

Proliferation analysis by a dye dilution

细胞增殖分析

染料稀释法

To demonstrate a dye dilution assay can be used to estimate the doubling time of cell lines in both monoculture and coculture. Conclusion: We quantitatively analyzed the proliferation of cell lines b

NIAID Data Ecosystem20

Mitochondria-Accumulating Rhenium(I) Tricarbonyl Complexes Induce Cell Death via Irreversible Oxidative Stress and Glutathione Metabolism Disturbance

抗癌药物机制

线粒体靶向

Mitochondria play a critical role in tumorigenesis. Targeting mitochondria and disturbing related events have been emerging as a promising way for chemotherapy. In this work, two binuclear rhenium(I)

Figshare2019-03-27 更新20

Effect of Periplocymarin on Gene Expression in Gastric Cancer Cell Lines HGC27 and MKN45. Effect of Periplocymarin on Gene Expression in Gastric Cancer Cell Lines HGC27 and MKN45

胃癌基因表达

抗癌药物机制

Periplocymarin (PPM) is an extract isolated from the traditional plant Periploca sepium with a cardiac glycoside-like structure. Previous studies have gradually revealed the anticancer potential of PP

NIAID Data Ecosystem20

TKIs time dependently stimulate DNA-synthesis but fail to increase cell numbers.

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