Specific families of pattern recognition receptors are responsible for detecting microbial pathogens and generating innate immune responses. Toll-like receptors (TLRs) are membrane-bound receptors ide
Interleukin-7 (IL-7) was discovered in the year 1988 as a factor that enhanced the growth of murine B-cell precursors in bone marrow culture system. It was also known as lymphopoietin 1and pre-B cell
(A) IL-8 production at 24 hours by AGS cells in response to IL-22 and IL-17A as measured by ELISA. p-value is based on ANOVA test with Dunnett’s correction for multiple comparisons ***p
This network was assembled automatically by INDRA (http://indra.bio) by processing all available biomedical literature with multiple machine reading systems, and integrating curated pathway databases.
Microglia are the major brain-resident immune cell subsetthat areessential during pathology and physiology in the central nervous system. The regulation of functional elementsrequired for microglialho