Crystal structure of JAK3 complexed with a potent ATP site inhibitor showing high selectivity within the Janus kinase family
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Crystal structure of JAK3 complexed with a potent ATP site inhibitor showing high selectivity within the Janus kinase family Descriptor: 3-(1H-indol-3-yl)-4-[2-(4-oxopiperidin-1-yl)-5-(trifluoromethyl)pyrimidin-4-yl]-1H-pyrrole-2,5-dione, Tyrosine-protein kinase JAK3 Authors: Tavares, G.A, Thoma, G, Zerwes, H.-G, Kroemer, M. Deposit date: 2010-11-09 Release date: 2010-12-29 Last modified: 2024-02-21 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Identification of a Potent Janus Kinase 3 Inhibitor with High Selectivity within the Janus Kinase Family. J.Med.Chem., 54, 2011
创建时间：
2010-11-09
