Quiescent ovarian cancer cells, in response to chemotherapy, secrete follistatin to induce chemotherapy resistance in surrounding cells.
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE210439
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We sought to identify mechanism of NFATC4 quiescence-driven chemoresistance. RNA-Seq identified upregulation of follistatin (FST) in quiescent OvCa cells. Comparative gene expression profiling analysis of HEY1 and SKOV3 cell lines expressing the IcNFATC4 or ILUC constructs were treated for 24, 48 and 96h with 100 ng/mL doxycyclin
创建时间：
2023-12-07
