Crystal structure of the second bromodomain of human TAF1 in complex with BAY-299 chemical probe
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Crystal structure of the second bromodomain of human TAF1 in complex with BAY-299 chemical probe Descriptor: 1,2-ETHANEDIOL, 6-(3-oxidanylpropyl)-2-(1,3,6-trimethyl-2-oxidanylidene-benzimidazol-5-yl)benzo[de]isoquinoline-1,3-dione, Transcription initiation factor TFIID subunit 1 Authors: Tallant, C, Bouche, L, Holton, S.J, Fedorov, O, Siejka, P, Picaud, S, Krojer, T, Srikannathasan, V, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Hartung, I.V, Haendler, B, Muller, S, Huber, K.V.M, Structural Genomics Consortium (SGC) Deposit date: 2016-11-20 Release date: 2017-05-03 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (1.75 Å) Cite: Benzoisoquinolinediones as Potent and Selective Inhibitors of BRPF2 and TAF1/TAF1L Bromodomains. J. Med. Chem., 60, 2017
创建时间：
2016-11-20
