Comparison of beta-Galactosidases from Normal and Operator Constitutive Strains of E. Coli Comparison of beta-Galactosidases from Normal and Operator Constitutive Strains of E. Coli

Contributor(s): Craven, Gary Steers, Edward, Jr., 1937- Anfinsen, Christian B. (Christian Boehmer), 1916-1995 Proceedings of the National Academy of Sciences of the United States of America Publication: National Academy Press (U.S.), October 1965 Language(s): English Format: Text Subject(s): Protein Renaturation beta-Galactosidase Peptide Mapping Genre(s): Archival Materials Articles Abstract: This brief article, Steers, Craven, and Anfinsen reported the results of various physical and chemical studies involving enzymatic comparisons of the lactose splitting enzyme beta-galactosidases from the "normal," or "wild type," and "operator constitutive" strains of E. coli. They determined that no detectable differences could be found between the two protein preparations, and concluded that the operator locus, the region of DNA at one end of an operon that acts as the binding site for repressor proteins, did not specify any part of the structure of the beta-galactosidase molecule. Copyright: This item may be under copyright protection; contact the copyright owner for permission before re-use. Extent: 8 pages NLM Unique ID: 101584571X169 (See in Profiles in Science) Profiles in Science ID: KKBBLC Permanent Link: http://resource.nlm.nih.gov/101584571X169 Archival Collection: The Christian B. Anfinsen Papers (Profiles in Science)