five

Genetic Polymorphism oriented PhaseI Study of Irinotecan and Doxifluridine for Unresectable or Recurrent Colorectal Cancer

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NIAID Data Ecosystem2026-03-06 收录
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https://www.omicsdi.org/dataset/ecrin-mdr-crc/2617574
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Interventions: Patients received treatment for 12 weeks. CPT-11 was administered once every two weeks in 500 ml of normal saline or dextrose via 120-min intravenous infusion on day 1, 15, 29, 43, 57 and 71. 5-DFUR was given as 200-mg capsules, two capsules were administered orally in the morning and evening after a meal on 5 consecutive days followed by a 2-day washout during the 12-week treatment period. Primary endpoint: MTD, DLT, recomended dose Study Design: Single arm Non-randomized
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2005-01-15
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