Compounds Related to FLC and Assayed for Inhibition of FLC Import.
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aAll compounds were tested at 100x molar excess to FLC for their effect
bFluorescein-labeled itraconazole was prepared by J. Liu and collaborators (unpublished data), and has no anti-Candida activity (T. White and collaborators, unpublished data).
cTipifarnib, an anti-cancer drug and the Tipifarnib analog JK11 (compound 2g) are both potent inhibitors of C14-demethylase, the target of the azole drugs [23].
dSTN54 is a dialkyl-imidazole with very potent activity against C14-demethylease, the target of the azole drugs [24].
创建时间:
2010-09-30



