Compounds Related to FLC and Assayed for Inhibition of FLC Import.

aAll compounds were tested at 100x molar excess to FLC for their effect bFluorescein-labeled itraconazole was prepared by J. Liu and collaborators (unpublished data), and has no anti-Candida activity (T. White and collaborators, unpublished data). cTipifarnib, an anti-cancer drug and the Tipifarnib analog JK11 (compound 2g) are both potent inhibitors of C14-demethylase, the target of the azole drugs [23]. dSTN54 is a dialkyl-imidazole with very potent activity against C14-demethylease, the target of the azole drugs [24].