Epigenetic reprogramming in adaptive drug resistance to BRAF inhibitor therapy
收藏NIAID Data Ecosystem2026-03-13 收录
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE156302
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资源简介：
The development of drug resistance is a major limiting factor to the efficacy of BRAF inhibitor therapy for melanoma. The goal of this study was to identify and characterize pathways that contribute to adaptive drug resistance to BRAF inhibitors. Venurafenib resistant cells were derived and profiled. Cells harboring specific genetic changes were also generated and profiled to identify and characterize relevant mechanisms.
创建时间：
2022-01-01
