Supplementary Table S1 from Mutation Drivers of Immunological Responses to Cancer
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Supplementary Table S1 - Regions identified by domainXplorer as associated with changes in immune infiltrate Columns are as follows: Symbol: official gene symbol Region: Region of the protein involved where ENSPXXXX is the protein isoform, ND/PFXXX/IDR is the type of region (ND: new domain / PF: PFAM domain / IDR: disordered region) and the numbers are the coordinates of the start and end of the region p1: p value of the linear regression model p2: p value of the wilcoxon test comparing samples with mutations in the region and samples with no mutations in the protein p3: p value of the wilcoxon test comparing samples with mutations in the region and samples with other mutations in the protein Mean F: Mean ESTIMATE immune score in samples with mutations in the region Mean OG: Mean ESTIMATE immune score in samples with mutations in the other regions of the gene Mean WT: Mean ESTIMATE immune score in samples with no mutations in the protein



