Estrogen Receptor Alpha Ligand Binding Domain in Complex with OP1154
收藏Protein Data Bank Japan2023-10-04 更新2026-03-21 收录
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https://pdbj.org/mine/summary/5ufw
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资源简介：
Estrogen Receptor Alpha Ligand Binding Domain in Complex with OP1154 Descriptor: (2S)-3-(4-hydroxyphenyl)-4-methyl-2-(4-{2-[(3S)-3-methylpyrrolidin-1-yl]ethoxy}phenyl)-2H-1-benzopyran-7-ol, Estrogen receptor Authors: Fanning, S.W, Hodges-Gallagher, L, Myles, D.C, Sun, R, Fowler, C.E, Green, B.D, Harmon, C.L, Greene, G.L, Kushner, P.J. Deposit date: 2017-01-06 Release date: 2018-01-10 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (1.583 Å) Cite: Specific stereochemistry of OP-1074 disrupts estrogen receptor alpha helix 12 and confers pure antiestrogenic activity. Nat Commun, 9, 2018
创建时间：
2017-01-06
