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Female human iPS cells retain an inactive X-chromosome

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NIAID Data Ecosystem2026-03-11 收录
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Comparison of human iPSC lines, ESC and fibroblasts to determine their expression patterns. All early passage female lines profiled expressed XIST RNA which is an indicator of an inactive X chromosome. Genes on the X-chromosome were also analyzed for overall levels of gene expression compared to human fibroblasts. hiPSC lines were generated and extracted for RNA with TriZOL and hybridization on Affymetrix arrays.

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2019-03-25
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