Mindful Body Awareness Training for MOUD - Baseline

The national opioid epidemic requires development of real-world evidence-based treatments for opioid use disorder, including adjuncts to Medication for Opioid Use Disorder (MOUD). Interventions are needed that address the complex needs of patients with opioid use disorder, which include substantial mental health co-morbidity and high rates of chronic pain. This study tests a promising mind-body intervention, Mindful Awareness in Body-oriented Therapy (MABT), as an adjunct to MOUD across multiple community outpatient clinical settings. MABT, a novel mindfulness-based intervention, uniquely addresses aspects of awareness, interoception, and regulation that may be associated with pain, mental health distress, and behavioral control that increase risk of relapse and poor treatment outcomes. Using a randomized, two-group, repeated measures design, we will compare those who receive MABT+ MOUD to MOUD only. The specific aims are to evaluate the effectiveness of MABT + MOUD compared to MOUD only to: a) reduce opioid use and other illicit substances; 2) improve mental and physical health; and 3) improve interoceptive awareness and mindfulness skills. A two-group (n = 165/165), randomized controlled repeated measures design will be employed. Assessments will be administered at baseline, post-intervention (3 months from baseline), and at 6, 9, and 12 months. Results of this study will inform the evidence base for behavioral treatment adjuncts to MOUD. This submission is the baseline data.