Genome sequencing from MCF-7 breast cancer cell line

MCF-7 breast cancer BAC array (Amplicon Express) and ATCC mammalian cell line The MCF-7 breast cancer cell line originated from a 69-year-old Caucasian woman who previously underwent two mastectomies in a five-year span. The tissue removed at the first mastectomy was benign, but the second operation found a malignant adenocarcinoma. Over a period of three years the woman was treated for local recurrences by radiotherapy and hormonotherapy. After the removal of nodules in the chest wall, a pleural effusion was discovered. The MCF-7 cell line was derived from this pleural effusion in 1970.