Functional and molecular characterization of mouse Gata2-independent hematopoietic progenitors

ChEBI2015-12-22 更新2026-07-12 收录

造血祖细胞

转录因子功能研究

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Functional and molecular characterization of mouse Gata2-independent hematopoietic progenitors

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2015-12-22

Foxf2 plays a dual role during TGFb-induced EMT by promoting apoptosis yet enabling cell junction dissolution and migration.. Foxf2 plays a dual role during TGFb-induced EMT by promoting apoptosis yet enabling cell junction dissolution and migration.

上皮-间质转化机制

转录因子功能研究

We have identified the transcription factor forkhead box protein F2 (Foxf2) to be upregulated in its expression during the EMT process and studied its functional contribution to EMT by siRNA-mediated

NIAID Data Ecosystem50

A Congenital Anemia Dissociates the Pleiotropic Functions of Master Transcription Factor GATA1 [G1E_ATACseq]

先天性贫血分子机制

转录因子功能研究

Master regulators, such as the hematopoietic transcription factor GATA1, have numerous roles in lineage commitment and differentiation. While human GATA1 mutations result in several blood diseases, al

NIAID Data Ecosystem40

Investigate the effect of gain of HAND2 on chromatin accessibility.

染色质可及性分析

转录因子功能研究

The overexpression of HAND2 in IMR32 cells results in a increase of chromation accessibility at the HAND2 and MYCN common binding sites. Overall design: In the HAND2 stably transfected IMR32 cells (IM

NIAID Data Ecosystem20

Gene expression analysis of mouse pancreas carrying Prox1 ectopic acinar expression

胰腺基因表达

转录因子功能研究

RNA sequencing was used to identify gene expression changes in pancreatic acinar cells with ectopic expression of the homeodomain transcription factor Prox1 Overall design: The pancreas P7 control mic

NIAID Data Ecosystem40

Competing dynamic gene regulatory networks involved in fibroblast reprogramming to haematopoietic progenitor cells [scRNA-Seq]

细胞重编程

造血祖细胞

Direct reprogramming of somatic cells offers a potentially safer therapeutic approach to generate patient-specific haematopoietic cells. However, this strategy is limited by stochasticity of reprogram

NIAID Data Ecosystem30

Functional and molecular characterization of mouse Gata2-independent hematopoietic progenitors

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