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G-CSF SECRETED BY EPIGENETICALLY REPROGRAMMED MUTANT IDH1 GLIOMA STEM CELLS, REVERSES THE MYELOID CELLS'-MEDIATED IMMUNOSUPPRESSIVE TUMOR MICROENVIRONMENT [Run1736]

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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE152274
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The purpose of this study was to characterize the molecular phenotype and function of tumor-infiltrating myeloid cells isolated from genetically engineered glioma mouse model expressing wild-type IDH1 or mutated IDH1 (isocitrate dehydrogenase). Two groups of tumor infiltrating myeloid cells were isolated: mutant IDH tumor and wild type IDH tumor; three samples pre group.
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2021-10-01
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