Consistency of empirical data with IAM based on the Dopamine receptor D4 (<i>DRD4</i>) alleles data.

Empirical and expected values by treating each of the four subpopulations as an isolated population following IAM for mutation. Data are shown in Table A (S5 Appendix). See Table 1 for the expected formulas and S4 Appendix for statistical methods to obtain empirical values. The proportional difference PD ≡ (expected value−estimated value)/expected value. All s.e. estimates were obtained by a bootstrap method based on 1000 resamples generated from the observed allele frequency distribution. #The expected parameters under IAM for the four subpopulations: Nμ = (1.0113, 1.6552, 2.2610, 2.1280); see Eq 1. Consistency of empirical data with IAM based on the Dopamine receptor D4 (DRD4) alleles data.