Investigating the alteration of membrane properties caused by doxorubicin: application of phospholipid mono- and bilayer biomembrane models.

This study shows the effects of doxorubicin (DOx) on DMPC monolayers formed at the air–water interface and bilayers formed at the gold-solution interface. Monolayer studies were performed usin Langmuir technique supplemented with polarization modulation infrared reflection absorption spectroscopy (PM-IRRAS) at the air-water interface. Supported bilayers were visualized by atomic force microscopy (AFM) and characgterized by electrochemical measurements and PM-IRRAS studies of supported bilayers.The dataset contains files (text and tiff files) showing the experimental results included in the publication. Please consult the readme.txt file for additional information and a more detailed description of each txt and tif file.