Profiling of TGF-beta regulated genes in immortal and tumor cell-lines. Homo sapiens

The study was carried out to delineate distinct TGF-beta target genes in immortal fibroblasts (HFhTERT), transformed fibroblasts (hFhTERT-LTgRAS) and tumor cells (HT1080). The data would help us in understanding the dual nature of TGF-beta. Overall design: Control_HF_1hr vs TGFb_HF_1hr, Control_HF_4hr vs TGF-b_HF_4hr, Control_HF_12hr vs TGF-b_HF_12hr, Control_HT_1hr vsTGF-b_HT_1hr, Control_HT_4hr vs TGF-b_HT_4hr, Control_HT_12hr vs TGF-b_HT_12hr, Control_LTgRAS_1hr vsTGF-b_LTgRAS_1hr, Control_LTgRAS_4hr vsTGF-b_LTgRAS_4hr, Control_LTgRAS_12hr vsTGF-b_LTgRAS_12hr