Crystal structure of Grp94 N-terminal domain bound to the purine inhibitor PU-H36
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Crystal structure of Grp94 N-terminal domain bound to the purine inhibitor PU-H36 Descriptor: 9-(pent-4-yn-1-yl)-8-[(2,4,6-trimethylphenyl)sulfanyl]-9H-purin-6-amine, Endoplasmin, GLYCEROL, ... Authors: Que, N.L.S, Gewirth, D.T. Deposit date: 2023-07-07 Release date: 2024-11-06 Last modified: 2025-02-19 Method: X-RAY DIFFRACTION (2.79 Å) Cite: Selective Inhibition of hsp90 Paralogs: Uncovering the Role of Helix 1 in Grp94-Selective Ligand Binding. Proteins, 93, 2025
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2023-07-07
