In vivo infectivity of pbicp-parasites was determined by parasite prepatency. Mice (5–10 per treatment group) were infected with 5×103 PbICPcontrol, PbICPcond, PbICPKO, or PbICPcomp salivary gland spo
aWorm burden recovered from mice immunization with one, two or three doses. For each vaccinated group: n = 10 mice. Comparison between total worm burden recoveredb or numbers of eggs per gram of intes
Background/ObjectivesHuman leishmaniases are parasitic diseases causing severe morbidity and mortality. No vaccine is available and numerous factors limit the use of current therapies. There is thus a
Note: F, female worm; M, male worm; n, the number of mice per group that survived the trial and were subjected to necropsy; ns, not significant.Parasitological data for rSjLD-vaccinated and control mi
