Structure of the human GluN1/GluN2A LBD in complex with N-ethyl-7-{[2-fluoro-3-(trifluoromethyl)phenyl]methyl}-2-methyl-5-oxo-5H-[1,3]thiazolo[3,2-a]pyrimidine-3-carboxamide (compound 29)
收藏Protein Data Bank Japan2024-11-06 更新2026-03-21 收录
下载链接：
https://pdbj.org/mine/summary/5i2n
下载链接
链接失效反馈官方服务：
资源简介：
Structure of the human GluN1/GluN2A LBD in complex with N-ethyl-7-{[2-fluoro-3-(trifluoromethyl)phenyl]methyl}-2-methyl-5-oxo-5H-[1,3]thiazolo[3,2-a]pyrimidine-3-carboxamide (compound 29) Descriptor: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, CALCIUM ION, GLUTAMIC ACID, ... Authors: Wallweber, H.J.A, Lupardus, P.J. Deposit date: 2016-02-09 Release date: 2016-03-16 Last modified: 2024-11-06 Method: X-RAY DIFFRACTION (2.12 Å) Cite: Discovery of GluN2A-Selective NMDA Receptor Positive Allosteric Modulators (PAMs): Tuning Deactivation Kinetics via Structure-Based Design. J.Med.Chem., 59, 2016
创建时间：
2016-02-09
