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Specific transcriptional programs differentiate ICOS and CD28 co-stimulatory signals in human naïve CD4 + T cells

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NIAID Data Ecosystem2026-03-14 收录
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a global transcriptome profiling was performed by RNA-seq on naïve CD4+ T cells upon ICOS or CD28 co-stimulation and bioinformatically was revealed a set of pathways specifically associated to each costimulatory molecule. exploitation of the RNA-Seq technology to compare gene transcription induced in naive Th cells by co-stimulation of either ICOS or CD28

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2022-10-04
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