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Disruption of Ras/cAMP signaling by perturbation of pathway elements and controlled cAMP concentration
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Markov State Models and Molecular Dynamics Simulations Reveal the Conformational Transition of the Intrinsically Disordered Hypervariable Region of K‑Ras4B to the Ordered Conformation
K-Ras4B, the most frequently mutated Ras isoform in human tumors, plays a vital part in cell growth, differentiation, and survival. Its tail, the C-terminal hypervariable region (HVR), is involved in
NIAID Data Ecosystem40
Identification of oncogenic Ras-regulated phosphorylation events that are concurrently regulated in adenocarcinoma A549 and H322 cells, but not in large cell carcinoma H1299 cells.
The regulated phosphorylation events are shown in Log2 scale. The relative phosphorylation levels with a 2-fold increase or decrease are indicated by bold font. The protein symbol, full name, and Swis
NIAID Data Ecosystem30
Additional file 3 of Proteomic analysis of murine norovirus-infected Raw 264.7 cells reveals the induction of Ras GTPases
Additional file 3.
NIAID Data Ecosystem20
Supplementary Table 7 from Combined Proteomic and Genetic Interaction Mapping Reveals New RAS Effector Pathways and Susceptibilities
Results from the "Paralog" sublibrary screen. Different metrics are reported on each of the three tabs of the spreadsheet as indicated. GI-T-Score : GIT Score; MWU Adj Pval: FDR of Mann-Whitney U Test
NIAID Data Ecosystem30
Microarray analysis of mice with thyroid hormone receptor and RAS mutations.
Affymetrix GeneChip Mouse Gene 1.0 ST Array was used to study gene expression profiles in three groups of mice: with thyroid hormone receptor ThrbPV (ThrbPV/PV) mutation only, with RAS mutation (KrasG
NIAID Data Ecosystem30
