Stat5a Core in complex with AK2292
收藏Protein Data Bank Japan2024-04-03 更新2026-03-28 收录
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Stat5a Core in complex with AK2292 Descriptor: DI(HYDROXYETHYL)ETHER, MALONATE ION, N-{5-[difluoro(phosphono)methyl]-1-benzothiophene-2-carbonyl}-3-methyl-L-valyl-L-prolyl-N-(5-{2-[(3R)-2,6-dioxopiperidin-3-yl]-1-oxo-2,3-dihydro-1H-isoindol-4-yl}pent-4-yn-1-yl)-N-methyl-N~3~-[4-(1,3-thiazol-2-yl)phenyl]-beta-alaninamide, ... Authors: Meagher, J.L, Stuckey, J.A. Deposit date: 2022-02-04 Release date: 2023-02-15 Last modified: 2024-04-03 Method: X-RAY DIFFRACTION (2.835 Å) Cite: A selective small-molecule STAT5 PROTAC degrader capable of achieving tumor regression in vivo. Nat.Chem.Biol., 19, 2023
创建时间：
2022-02-04
