Estimated number of episodes due to hospitalizations, and deaths due to Shigellae among older children and adults in Africa and South Asia using Method 2.

∧Median incidence data not available; review used SEAR incidence rates applied to AFR population to get total # annual episodes [6].∧∧2010 population among persons ≥5 yrs of age. Source: UN Population Division [9].*Calculated using weighted mean % positive from outpatient studies reporting >4 pathogens (i.e. ETEC: 4.6%; Shigellae: 9.3%) [6].**Calculated using proportion of annual cases due to Shigellae reported at a treatment facility (i.e. 0.053) [11].***Calculated by applying case fatality rate for hospitalized cases due to Shigellae (i.e. 0.33%) [11].