Mutant p53 Disrupts Mammary Acinar Morphogenesis via the Mevalonate Pathway

ChEBI2012-02-13 更新2026-07-21 收录

肿瘤代谢调控

乳腺发育

数据链接：

https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-31812 数据链接链接失效反馈

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资源简介：

Mutant p53 Disrupts Mammary Acinar Morphogenesis via the Mevalonate Pathway

创建时间：

2012-02-13

Prenatal exposure to bisphenol A, genistein and indole-3-carbinol on early mammary gland development and carcinogenesis in female Sprague-Dawley offspring

乳腺发育

致癌作用

Rodent studies have indicated that gestational and perinatal bisphenol A (BPA) exposure increase the risk of developing breast cancer during adulthood. In contrast, some dietary compounds such as geni

NIAID Data Ecosystem80

DUSP6 ablation restores CAR T fitness impaired by tumor CD58 loss through invigoration of AP-1 signaling

CART细胞疗法优化

肿瘤代谢调控

Primary resistance to chimeric antigen receptor (CAR) T-cell therapies limited its widespread applications. Our prior genome-wide CRISPR/Cas9 screening revealed loss of CD58 as a crucial tumor intrins

NIAID Data Ecosystem10

Effects of deletion of SAT1, a polyamine-metabolic enzyme, on mouse HeLa xenograft tumor

肿瘤代谢调控

多胺代谢与肿瘤微环境

An acidic tumor microenvironment plays a critical role in tumor progression. However, understanding of metabolic reprogramming of tumors in response to acidic extracellular pH has remained elusive. Us

NIAID Data Ecosystem00

Table_1_Nontoxic Targeting of Energy Metabolism in Preclinical VM-M3 Experimental Glioblastoma.DOCX

胶质母细胞瘤治疗

肿瘤代谢调控

Introduction: Temozolomide (TMZ) is part of the standard of care for treating glioblastoma multiforme (GBM), an aggressive primary brain tumor. New approaches are needed to enhance therapeutic efficac

NIAID Data Ecosystem20

An epigenetic memory of pregnancy in the mouse mammary gland

表观遗传调控

乳腺发育

An epigenetic memory of pregnancy in the mouse mammary gland

ChEBI2015-05-15 更新00