supplementary files for study entitled "Systematic review and meta-analysis of the efficacy and risk of adverse events of dupilumab in the treatment of prurigo nodularis"

• Real-world data reveal that dupilumab therapy for prurigo nodularis is effective and well tolerated in the short term, but ophthalmic adverse events frequently occur. • Clinical trials demonstrated that dupilumab is effective and safe for the treatment of prurigo nodularis in adults.