Structural basis for domain rotation during adenylation of active site K123 and fragment library screening against NAD+ -dependent DNA ligase from Mycobacterium tuberculosis
收藏Protein Data Bank Japan2023-11-29 更新2026-03-21 收录
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Structural basis for domain rotation during adenylation of active site K123 and fragment library screening against NAD+ -dependent DNA ligase from Mycobacterium tuberculosis Descriptor: (4R)-4-(4-fluorophenyl)-4,5,6,7-tetrahydro-1H-imidazo[4,5-c]pyridine, DNA ligase A, GLYCEROL, ... Authors: Ramachandran, R, Afsar, M, Shukla, A. Deposit date: 2020-02-07 Release date: 2021-02-10 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (2.401 Å) Cite: Structure based identification of first-in-class fragment inhibitors that target the NMN pocket of M. tuberculosis NAD + -dependent DNA ligase A. J.Struct.Biol., 213, 2021
创建时间：
2020-02-07
