Data of: Imputation-free reconstructions of three-dimensional chromosome architectures in human diploid single-cells using allele-specified contacts
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These files are results obtained in Imputation-free reconstructions of three-dimensional chromosome architectures in human diploid single-cells using allele-specified contacts by Yoshito Hirata, Arisa H. Oda, Chie Motono, Masanori Shiro & Kunihiro Ohta. There are 33 files for the corresponding each reconstruction of three-dimensional chromosomone structures for each cell. There are 3D structures for 15 GM cells and 18 PBMC cells, which are obtained from the single cell Hi-C data of Tan et al. Science (2018). For each file, there are 6 columns: The first column corresponds to the allele (0: maternal, 1: paternal) The second column corresponds to the chromosome (1-22: chromosome's number, 23: X, 24: Y) The third column corrsponds to the base point. The fourth column, the fifth column and the sixth column correspond to x-, y-, and z-axes of our reconstruction. Methods First, the single cell Hi-C data of Tan et al. (2018) have been downloaded from through GEO Series accession number GSE117876 at www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE117876. Then, we applied the proposed recurrence plot-based method here to reconstruct 3D chromosome structures of 33 cells (15 GM cells and 18 PBMC cells). The resulting 3D chromosome structures are deposited here.



