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Transcriptional response of mce3R induction and ctpD disruption in Mycobacterium tuberculosis CDC1551

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NIAID Data Ecosystem2026-03-12 收录
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We identified mce3R and ctpD as genes that could alter M tuberculosis (Mtb) response to isoniazid when perturbed using a regulatory network-based TRIP screen [see associated data at PRJNA483505]. To investigate the mechanisms underlying this response, we performed RNAseq on genetically perturbed mutant strains either in the presence or absence of isoniazid.

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2021-02-24
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