Cerebellar Gene Expression Profile Analysis in a Rat Model of Acute Alcohol Intoxication

We first established a model of acute alcohol intoxication in SD rats, and then used rat cDNA microarray to profile mRNA expression in the cerebella of alcohol-intoxicated rats (experimental group) and saline-treated rats (control group).本研究首先构建了SD大鼠急性酒精中毒模型，随后采用大鼠cDNA微阵列（cDNA microarray）技术，对酒精中毒模型大鼠（实验组）与生理盐水处理大鼠（对照组）的小脑组织中的mRNA表达谱进行了分析。