Determine the role of TXNDC9 in hepatocellular carcinoma progression. Determine the role of TXNDC9 in hepatocellular carcinoma progression

Thioredoxin Domain Containing 9 (TXNDC9) is a member of the thioredoxin family. The exact function of this protein is not known. This experiment is a transcriptiome profiling of TXNDC9 dependent RNA expression in hepatocellular carcinoma cell line HepG2. By compairing the gene expression profile of WT and TXNDC9 knockout, we identified some genes directly or indirectly regulated by TXNDC9 in hepatocellular carcinoma. Overall design: RNA-seq analysis of wild Type and TXNDC9 knockout HepG2 cells