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Supplementary Data from ONC201 in Combination with Paxalisib for the Treatment of H3K27-Altered Diffuse Midline Glioma

NIAID Data Ecosystem2026-05-01 收录

神经肿瘤靶向治疗

胶质瘤药物联合疗法

数据链接：

https://figshare.com/articles/dataset/Supplementary_Data_from_ONC201_in_Combination_with_Paxalisib_for_the_Treatment_of_H3K27-Altered_Diffuse_Midline_Glioma/30700393 数据链接链接失效反馈

官方服务：

资源简介：

All Supplementary Tables

应用场景：

创建时间：

2023-07-14

神经肿瘤靶向治疗

癌症干细胞抑制

Glioblastoma multiforme (GBM) is a devastating disease yet no effective drug treatment has been established to date. Glioblastoma stem-like cells (GSCs) are insensitive to treatment and may be one of

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Focused Ultrasound-Induced Blood–Brain Barrier Opening to Enhance Temozolomide Delivery for Glioblastoma Treatment: A Preclinical Study

神经肿瘤靶向治疗

血脑屏障开放技术

The purpose of this study is to assess the preclinical therapeutic efficacy of magnetic resonance imaging (MRI)-monitored focused ultrasound (FUS)-induced blood-brain barrier (BBB) disruption to enhan

NIAID Data Ecosystem20

Mutant IDH inhibitors induce lineage differentiation in IDH-mutant Oligodendroglioma II

神经肿瘤靶向治疗

癌细胞机制

A subset of patients with IDH-mutant glioma respond to inhibitors of mutant IDH (IDHi), yet the molecular underpinnings of such responses are not understood. Here, we profiled by single-cell or single

NIAID Data Ecosystem10

Combined inhibition of TOP1 and PARP: a synergistic therapeutic strategy for PTEN-deficient glioblastoma. Combined inhibition of TOP1 and PARP: a synergistic therapeutic strategy for PTEN-deficient glioblastoma

神经肿瘤靶向治疗

DNA损伤修复

Deletions or loss-of-function mutations in phosphatase and tensin homolog (PTEN) are common in glioblastoma (GBM) and have been associated with defective DNA damage repair. Here we investigated whethe

NIAID Data Ecosystem20

Table 1 from Combining Brigatinib with mTOR Inhibition to Effectively Treat NF2-SWN–Associated and Sporadic NF2-Deficient Meningiomas

神经肿瘤靶向治疗

临床前药效评价

The relative response of AG-NF2-Luc2 tumor xenografts in mice prior to and after treatment with vehicle, brigatinib, INK128, or brigatinib + INK128.

Figshare2026-01-27 更新10