Liver organoids generated from individuals carrying PiZZ variant of alpha-1-antitrypsin contain high lipid content. Liver organoids generated from individuals carrying PiZZ variant of alpha-1-antitrypsin contain high lipid content

We generated hepatic organoids from MZ and ZZ patients with the aim to investigate their lipid status To discover genes related to lipid metabolism likely involved in lipid deposits. Overall design: Comparative gene expression analysis of RNA-seq data of hepatic organoids derived from alpha-1 antitrypsin deficiency