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慢性肝病期间肝窦内皮细胞的转录组揭示了阶段特异性分泌特征

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干细胞与再生医学数据中心2023-02-10 更新2024-03-06 收录
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In this study RNAseq was used for studying the transcriptome profile of primary liver sinusoidal endothelial cells (LSECs) isolated from non-lesioned non-tumorous liver tissues (considered as healthy) and from cirrhotic liver explants (ethanol etiology). Results showed different transcriptomic profile between two populations of LSECs with 1374 significant deregulated genes (fold-change>1.5 and p-vale<0.05) in cirrhotic-LSECs compared with healthy-LSECs.
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2023-02-10
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