Table_1_Study on Isomeric Impurities in Cefotiam Hydrochloride.DOC
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https://figshare.com/articles/dataset/Table_1_Study_on_Isomeric_Impurities_in_Cefotiam_Hydrochloride_DOC/13578674
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资源简介：
In this study, two isomeric impurities were identified in cefotiam hydrochloride injection preparation and were characterized. Column-switching HPLC-MS and NMR techniques were used to identify the impurity 1 as the Δ3(4) isomers of cefotiam. Using software-based calculations, it was predicted that neither of the isomeric impurities was embryotoxic. This study provides a reference for the production, storage, and quality control of cefotiam and related cephalosporin antibiotics.
创建时间：
2021-01-15
