官方服务：
资源简介：
transcriptome sequencing of nucleus pulposus cells from ruptured intervertebral disc
应用场景：
创建时间：
2025-08-31
相关数据集
Ganoderic Acid A alleviates the degeneration of intervertebral disc via suppressing the activation of TLR4/NLRP3 signaling pathway
As a multifactorial disease, intervertebral disc degeneration (IVDD) causes many spinal-related diseases, which causes disability in the workforce and heavy social costs all over the world. Recently,
NIAID Data Ecosystem60
Reactive Oxygen Species promote Pyroptosis of Nucleus Pulposus Cells in Modic changes with disc herniation based on smart-RNA sequencing
We performed Smart-seq 2 and analyzed the differential expression of genes and pathways of Modic change to comparator group. Additionally, we detect the role of reactive oxygen species on pyroptosis o
NIAID Data Ecosystem40
Transcriptomic evaluation of ovine intervertebral disc cells as an in vitro model to explore degenerative processes
Intervertebral disc degeneration (IVDD) is a leading cause of chronic back pain and disability. Understanding the cellular and molecular mechanisms underlying disc degeneration is crucial for developi
NIAID Data Ecosystem20
stseranidou2024 - Nucleus Pulposus Cell Network Modelling in the Intervertebral Disc
ABSTRACT: Intervertebral disc degeneration (IDD) arises from an intricate imbalance between the anabolic and catabolic processes governing the extracellular matrix (ECM) within the disc. Bioch
NIAID Data Ecosystem40
Effect of recombinant Shh on gene expression of primary rat nucleus pulposus cells
In order to study the effect of recombinant Shh (rShh) on nucleus pulposus cells, primary nucleus pulposus cells from SD rats were obtained.Then, nucleus pulposus cells were treated with rShh at 200 n
NIAID Data Ecosystem30
