Additional file 1 of HDAC1/2 control mesothelium/ovarian cancer adhesive interactions impacting on Talin-1-α5β1-integrin-mediated actin cytoskeleton and extracellular matrix protein remodeling
Additional file 2: Table 1. KBTBD8 shRNA information. This table shows all the sequences and locations of human KBTBD8 shRNAs used in this study. shRNAs were cloned into the plasmid GV248 cutted by Ag
Ovarian cancer is an inflammation-associated malignancy with a high mortality rate. CXCR2 expressing ovarian cancers are aggressive with poorer outcomes. We therefore investigated molecular mechanisms
Interplay of RAC1, p38 MAPK, PAK1 and MMP2 in cell signaling pathways downstream of TEK receptor activity related to tumor growth, angiogenesis, and cell proliferation. These processes are reduced in
The cure rate for late stage epithelial ovarian cancer (EOC) has not significantly improved over several decades. New and more effective targets and treatment modalities are urgently needed. RNA-seq a
Advanced ovarian cancer is the most lethal gynecologic malignancy in the United States. Ovarian cancer cells are known to have diminished response to TGF-beta, but it remains unclear whether TGF-beta
