Data S1 - Soluble CD163 as a Marker of Macrophage Activity in Newly Diagnosed Patients with Multiple Sclerosis

File contains: Table S1 Table S1 includes Excel file and (double click to activate) contains all basic data for this paper. Abbreviations: RRMS (relapsing-remitting MS), PPMS (primary-progressive MS), SPMS (secondary-progressive MS), CIS (clinically isolated syndrome), SC (symptomatic controls with normal or abnormal MRI), n (number of persons), CSF (cerebrospinal fluid), y (years), d (days), Gender (1 = male; 2 = female), OND (other neurological disease), OMD (other medical disease). Table S2 Table S2 lists proteins, their respective molecular weight and ratio CSF/serum. The table is adapted from Nockher et al (22). Abbreviations: kDA (kilo Dalton). Table S3 Table S3 shows the output of our regression analysis on log transformed sCD163 serum values (lSerum) Table S4 Table S4 shows the output of our regression analysis on log transformed sCD163 CSF values (lcsv). Table S5 Table S5 shows the output of our regression analysis on log transformed scd163 CSF/serum values (lRatio). Table S6 Table S6 shows the output of our regression analysis on log transformed sCD163 index values (lIndex) Figure S1 Figure S1 shows the istribution of proteins and their CSF/serum ratios plotted against their molecular weight (in kD). This figure is adapted from Nockher et al (22). Proteins marked with (•) originate solely from the blood compartment (see appendix table 2 below) and proteins marked by (o) are suspected to be produced intrathecally.
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