Modifying the specificity of non-coding RNA molecules for silencing gene expression in eukaryotic cells
收藏国家林业和草原科学数据中心2023-02-12 更新2024-03-07 收录
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资源简介：
A method of modifying a gene encoding or processed into a non-coding RNA molecule having no RNA silencing activity in a eukaryotic cell， with the proviso that said eukaryotic cell is not a plant cell， is disclosed. The method comprising introducing into the eukaryotic cell a DNA editing agent conferring a silencing specificity of said non-coding RNA molecule towards a target RNA of interest. A method of modifying a gene encoding or processed into a RNA silencing molecule to a target RNA in a eukaryotic cell is also disclosed. Methods of disease prevention and treatment， methods of inducing cell apoptosis and methods of generating a eukaryotic non-human organism are also disclosed.
提供机构：
国家林业和草原科学数据中心
创建时间：
2023-02-12
