The FK1 domain of FKBP51 in complex with the macrocyclic SAFit analog m5(2,4)-H2

The FK1 domain of FKBP51 in complex with the macrocyclic SAFit analog m5(2,4)-H2 Descriptor: (2~{S},9~{S})-2-cyclohexyl-23,24-dimethoxy-11,17,21-trioxa-4-azatricyclo[20.3.1.0^{4,9}]hexacosa-1(26),22,24-triene-3,10-dione, Peptidyl-prolyl cis-trans isomerase FKBP5 Authors: Meyners, C, Spiske, M, Hausch, F. Deposit date: 2024-09-09 Release date: 2025-01-15 Last modified: 2025-03-19 Method: X-RAY DIFFRACTION (2.5 Å) Cite: Conformationally Restricted Macrocycles as Improved FKBP51 Inhibitors Enabled by Systematic Linker Derivatization. Angew.Chem.Int.Ed.Engl., 64, 2025