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Bayesian Adaptive Clinical Trials for Anti‐Infective Therapeutics during Epidemic Outbreaks

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NBER2020-05-01 更新2025-01-04 收录
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In the midst of epidemics such as COVID-19, therapeutic candidates are unlikely to be able to complete the usual multiyear clinical trial and regulatory approval process within the course of an outbreak. We apply a Bayesian adaptive patient-centered modelwhich minimizes the expected harm of false

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2020-05-01
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