Tenoxicam (TNX) belongs to the oxicam family of drugs popularly known as nonsteroidal anti-inflammatory drugs (NSAIDs). Its therapeutic action as a drug is limited by poor aqueous solubility (14 mg/L)
An anticancer drug, lenalidomide, has low oral bioavailability (below 33%) due to its poor solubility in water. To improve its solubility, three cocrystals of lenalidomide with urea (1) and 3,5-dihydr