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Parkinson's disease genes VPS35 and EIF4G1 interact genetically and converge on alpha-synuclein

ChEBI2014-12-19 更新2026-07-21 收录

帕金森病分子机制

神经退行性疾病基因

数据链接：

https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-64304 数据链接链接失效反馈

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Parkinson's disease genes VPS35 and EIF4G1 interact genetically and converge on alpha-synuclein

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创建时间：

2014-12-19

神经退行性疾病基因

单细胞脑组织测序

We have sequenced MSA brain as follows1. Mate pair sequence for one case, substantia nigra and cerebellum2. Exome sequences from 13 cases3. Single cell low coverage WGS, 170 cells passing QC and analy

NIAID Data Ecosystem100

Data_Sheet_1_Proteomics analysis of the p.G849D variant in neurexin 2 alpha may reveal insight into Parkinson’s disease pathobiology.docx

帕金森病分子机制

蛋白质组学分析

Parkinson’s disease (PD), the fastest-growing neurological disorder globally, has a complex etiology. A previous study by our group identified the p.G849D variant in neurexin 2 (NRXN2), encoding the s

NIAID Data Ecosystem50

In silico analysis of nicotine’s molecular targets in Parkinson’s disease

帕金森病分子机制

药物靶点发现

We aimed to elucidate the molecular processes involved in how nicotine affects PD.Toxicogenomic, molecular mechanisms, physicochemical properties, pharmacokinetic profile, and biological activity were

Figshare2025-06-25 更新30

In vivo repair of a protein underlying a neurological disorder by programmable RNA editing

神经退行性疾病基因

RNA靶向

The goal of this study is to determine the effects of targeted RNA editing in the hippocampus of a mouse model of Rett syndrome. Mice containing a patient G>A mutation in Methyl CpG binding Protein 2

NIAID Data Ecosystem80

Supplementary information files for "Parkinson’s associated protein DJ-1 regulates intercellular communication via extracellular vesicles in oxidative stress"

帕金森病分子机制

细胞外囊泡蛋白质组学

Supplementary files for article "Parkinson’s associated protein DJ-1 regulates intercellular communication via extracellular vesicles in oxidative stress"Mutations in DJ-1 cause autosomal recessive Pa

Figshare2025-11-21 更新40

Parkinson's disease genes VPS35 and EIF4G1 interact genetically and converge on alpha-synuclein

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