Determine the key protein modules and biomarker candidates characterizing each lung adenocarcinoma subtype together with genomic alterations of gene mutations and CNVs and to understand the tumourigen
Background: DNA methylation (MET)–mediated transcriptomic disturbance and copy number variations (CNVs) exert a significant influence in stimulating the heterogeneous progression of stomach adenocarci
Multi-layered genomic studies such as the TCGA project have greatly advanced our understanding on molecular pathogenesis of lung cancer. For Asian nonsmoker patients, however, majority of studies have